イベント

2009年12月 1日

12月8日（火）に第73回スポーツサイエンス研究会が開催されます

第73回スポーツサイエンス研究会
日時　12月8日（火）17:30〜18:30
場所　早稲田大学所沢キャンパス100号館　第1会議室

特別講演
演者：Dr. Zsolt RADAK (Semmelweis University, Budapest, Hungary)
演題：Exercise and Hormesis
内容
Physical inactivity leads to increased incidence of a variety of diseases and
it can be regarded as one of the end points of the exercise-associated
hormesis curve. On the other hand, regular exercise, with moderate
intensity and duration, has a wide range of beneficial effects on the body
including the facts that it improves cardio-vascular function, partly by a
nitric oxide mediated adaptation, and may reduce the incidence of
Alzheimer's disease by enhanced concentration of neurotrophins and by the
modulation of redox homeostasis. In addition, it appears that oxidation of
guanine in DNA, RNA and telomere can also described by hormetic dose
response. Exercise-induced repair of DNA damage varies in nucleus and
mitochondria, which could have special role in oxidative stress related
adaptation. Single bouts of exercise increase, and regular exercise decreases
the oxidative challenge to the body, whereas excessive exercise and
overtraining lead to damaging oxidative stress and thus are an indication of
the other end point of the hormetic response. Based upon the genetic setup,
regular moderate physical exercise/activity provides systemic beneficial
effects, including improved physiological function, decreased incidence of
disease and a higher quality of life.

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